@article{CCO28852,
author = {Yoshikuni Kawaguchi and Jenilette D. Velasco and Elsa M. Arvide and Steven H. Wei and Jean-Nicolas Vauthey},
title = {Interactions of multiple gene alterations in colorectal liver metastases},
journal = {Chinese Clinical Oncology},
volume = {8},
number = {5},
year = {2019},
keywords = {},
abstract = {The advancements in next generation sequencing have expanded the information available in clinical practice. Alterations of TP53, APC, RAS, PIK3CA, and SMAD4 are present in more than 10% of patients with colorectal liver metastases (CLM). Of these genes, TP53, RAS and SMAD4 were associated with worse survival in patients undergoing CLM resection. Testing multiple gene alterations provides a more precise prognosis for patients undergoing CLM resection and may be useful for better clinical decision making},
issn = {2304-3873}, url = {https://cco.amegroups.org/article/view/28852}
}