Abstract
AB026. A rare case report: multiple hemangioblastoma
Wa Ode Nur Intan Octina1, Dessika Rahmawati2
1Department of Neurology, Faculty of Medicine, Brawijaya University, Malang, Indonesia;
2Division of Neurooncology, Department of Neurology, Faculty of Medicine, Brawijaya University, Malang, Indonesia
Correspondence to: Wa Ode Nur Intan Octina, MD. Neurology Resident, Department of Neurology, Faculty of Medicine, Brawijaya University, Veteran Street, Malang 65145, East Java, Indonesia. Email: wdnurintanoct@student.ub.ac.id.
Background: Hemangioblastomas (HBLs) are uncommon tumors of the central nervous system (CNS), corresponding to 1% to 2.5% of all intracranial tumors. They can present sporadically or in patients with von Hippel-Lindau (VHL) disease along with a variety of benign and malignant tumors, and are most often located in the cerebellum, brainstem, and spinal cord. Although surgical resection is currently considered the main therapeutic option for symptomatic lesions, evidence supporting the application of microsurgery has not been systematically assessed. However, post-operative outcomes can vary depending on factors including disease location, number of lesions, and tumor characteristics that make complete resections difficult. The objective of this case report is to document a rare case of multiple HBL in a 45-year-old man, highlighting the need for further research, the absence of a standardized treatment protocol for appropriate management strategies.
Case Description: A 45-year-old man presented to the outpatient neurology department with a chief complaint of gradual weakness of the left side of his body, walking unsteadily, and seizure. Neurological examination revealed a positive dysmetria sign. According to his medical records, he was diagnosed with multiple HBL since August 2022 and subsequently underwent two times partial tumor resections, and a ventriculoperitoneal (VP)-shunt due to hydrocephalus. The latest magnetic resonance imaging examination shows improvement in the original tumor. He is currently receiving symptomatic therapy with complaints have improved.
Conclusions: This case report highlights a rare occurrence of multiple HBL in a 45-year-old man. Surgical management of HBL was the most common modality and was suggested as an effective and optimal treatment, but the recurrence possibility of the cystic wall tumor must also be considered in the choice of treatment.
Keywords: Multiple hemangioblastoma (multiple HBL); a rare case; case report
Acknowledgments
Funding: None.
Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://cco.amegroups.com/article/view/10.21037/cco-24-ab026/coif). The authors have no conflicts of interest to declare.
Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. All procedures performed in this study were in accordance with the ethical standards of the institutional and/or national research committee(s) and with the Helsinki Declaration (as revised in 2013). Written informed consent was obtained from the patient for the publication of this case report and accompanying images. A copy of the written consent is available for review by the editorial office of this journal.
Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the noncommercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.
Cite this abstract as: Octina WONI, Rahmawati D. AB026. A rare case report: multiple hemangioblastoma. Chin Clin Oncol 2024;13(Suppl 1):AB026. doi: 10.21037/cco-24-ab026
