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New Impact Factor for Chinese Clinical Oncology: 2.7

We are pleased to announce that the Chinese Clinical Oncology (CCO) has attained its latest impact factor for the 2025 citation year: 2.7.

Chinese Clinical Oncology 2025 CiteScore Released: 3.4

We are pleased to announce that the Chinese Clinical Oncology (CCO) has achieved its 2025 CiteScore: 3.4, ranking 248 out of 428 journals in the Oncology category. This milestone underscores our ongoing commitment to publishing impactful research in the field.

Interviews with Outstanding Authors (2026)

In 2026, many CCO authors make outstanding contributions to our journal. Their articles published with us have received very well feedback in the field and stimulate a lot of discussions and new insights among the peers.

Hereby, we would like to highlight some of our outstanding authors who have been making immense efforts in their research fields, with a brief interview of their unique perspective and insightful view as authors.

CCO Annual Report (2025)

We are glad to present a brief introduction of CCO’s progress in 2025 here. CCO has an international editorial board comprising 56 members from 14 countries, including USA (50%), China (9%), Italy (9%), Japan (7%), among others. CCO published 80 articles in 2025, including 18 Review Articles and 28 Original Articles in total. According to the Google Analytics, CCO journal website had all together 169,133 visitors worldwide and 366,280 pageviews in 2025.

AME and Wolters Kluwer aim to expand access to global medical research through new collaboration

The agreement broadens the reach of nearly 50 Open Access titles, contributing globally to over 5,000 articles

October 2, 2025 — Wolters Kluwer Health announced a new collaboration with AME Publishing Company, an Open Access publisher specializing in medical journals and books, headquartered in Hong Kong, China.

Interviews with Editorial Board Members

CCO features a distinguished editorial board, the members of which continue to instill the power of their expertise for the journal’s development. By launching this column, we are glad to introduce to you some of them in the form of interviews, in which they will share their unique career experiences and perspectives. We believe their insights will shed light on the knowledge of related fields.

Interviews with Guest Editors

Over the years, a number of CCO guest editors have made valuable contributions to the journal. This column features interviews with our guest editors, who graciously share their experience in scientific careers and provide insightful perspectives on the special series.

Reviewer of the Month (2025)

In 2025, CCO reviewers continue to make outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.

Hereby, we would like to highlight some of our outstanding reviewers, with a brief interview of their thoughts and insights as a reviewer. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

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Vol 15, No 3 (June, 2026)

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Original Article

Network pharmacology of Sijunzi decoction in pancreatic cancer

Rujia Zheng, Qitai Chen, Mengting Zhang, Xishan Yang, Yi Zang, Zhe Zhang

Chinese Clinical Oncology

2026;

(3)

:41

(30 June 2026)

PDF Full Text (23) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Efficacy and safety of TAS-102 followed by regorafenib or reverse sequence in later-line treatment of metastatic colorectal cancer: a systematic review and meta-analysis

Bannawich Sapapsap, Sirapratch Champarhorm, Anchana Pongpun, Nattapong Kanchana, Jittipon Tantivit, Nattawut Leelakanok

Chinese Clinical Oncology

2026;

(3)

:42

(30 June 2026)

PDF Full Text (49) Reporting Checklist Peer Review File COI Form Open Access

Review Article

Optimizing media composition for patient-derived organoids in ovarian cancer: a narrative review

Kattreen Hanna, Mayerly Castrillón Sánchez, Gabriel Levin, Gaëlle Akiki, Basile Tessier-Cloutier, Shuk On Annie Leung

Chinese Clinical Oncology

2026;

(3)

:43

(30 June 2026)

PDF Full Text (73) Reporting Checklist Peer Review File COI Form Open Access

Differentiating glioma recurrence from radiation necrosis: a narrative review of positron emission tomography and magnetic resonance imaging and their diagnostic accuracies

David Leen, Monica Wong, Eddie Lau, Sweet Ping Ng

Chinese Clinical Oncology

2026;

(3)

:44

(30 June 2026)

PDF Full Text (19) Reporting Checklist Peer Review File COI Form Open Access

Biliary neuroendocrine tumors: a narrative review of current diagnostics and management strategies

Hima B. Darapu, Ashish Manne, Anup Kasi, Ravi Kumar Paluri

Chinese Clinical Oncology

2026;

(3)

:45

(30 June 2026)

PDF Full Text (11) Reporting Checklist Peer Review File COI Form Open Access

Epidemiology, diagnosis, and treatment of primary pulmonary mucosa-associated lymphoid tissue lymphoma

Gabriele Sapuppo, Sara Frazzetto, Maria Cristina Pirosa, Emanuele Zucca

Chinese Clinical Oncology

2026;

(3)

:46

(30 June 2026)

PDF Full Text (15) Peer Review File COI Form Open Access

Case Report

Drug-induced liver injury and acute pancreatitis during trastuzumab therapy in a BRCA1-mutated, HER2-positive breast cancer patient: a case report

Karolina Kinga Kruczkowska, Natalie Gąsiorek, Robert Wiraszka

Chinese Clinical Oncology

2026;

(3)

:47

(30 June 2026)

PDF Full Text (15) Reporting Checklist Peer Review File COI Form Open Access

Editorial Commentary

Combination therapy in sarcomas and the challenges of heterogeneity

Emine Hatipoglu, Robin L. Jones

Chinese Clinical Oncology

2026;

(3)

:48

(30 June 2026)

PDF Full Text (12) Peer Review File COI Form Open Access

Back to the future: “7+3” joins the venetoclax plus intensive chemotherapy movement

Michael Canonico, Somedeb Ball

Chinese Clinical Oncology

2026;

(3)

:49

(30 June 2026)

PDF Full Text (20) Peer Review File COI Form Open Access

Clonal hematopoiesis in breast cancer: moving beyond prevalence toward clinical relevance

Farah Shah, Catherine C. Coombs

Chinese Clinical Oncology

2026;

(3)

:50

(30 June 2026)

PDF Full Text (14) Peer Review File COI Form Open Access

Age, endocrine therapy persistence, and recurrence risk in hormone receptor-positive early breast cancer: clarifying a long-standing clinical question

Marcus Schmidt

Chinese Clinical Oncology

2026;

(3)

:51

(30 June 2026)

PDF Full Text (11) Peer Review File COI Form Open Access

Can recurrence-free survival replace overall survival for resectable esophageal cancer?

Jane E. Rogers, Jaffer A. Ajani

Chinese Clinical Oncology

2026;

(3)

:52

(30 June 2026)

PDF Full Text (25) Peer Review File COI Form Open Access

Adjuvant CDK4/6 inhibitors and novel therapies in early breast cancer: lessons from monarchE overall survival data

Tatsunori Shimoi

Chinese Clinical Oncology

2026;

(3)

:53

(30 June 2026)

PDF Full Text (20) Peer Review File COI Form Open Access

Venetoclax with intensive chemotherapy in acute myeloid leukemia

Logan Shaver, Omer Jamy

Chinese Clinical Oncology

2026;

(3)

:54

(30 June 2026)

PDF Full Text (16) Peer Review File COI Form Open Access

Letter to the Editor

Toxicity management in thoracic chemoradioimmunotherapy: pirfenidone for low grade pneumonitis and lung fibrosis

Franz Zehentmayr, Elvis Ruznic, Raphaela Moosbrugger, Brane Grambozov

Chinese Clinical Oncology

2026;

(3)

:55

(30 June 2026)

PDF Full Text (31) Peer Review File COI Form Open Access

Guidelines and Expert Consensus

Guidelines on the diagnosis and treatment of primary liver cancer (2011 edition)

Primary Liver Cancer Diagnosis Treatment Expert Panel

Published online: 01 September 2012

PDF Full Text (130679) Open Access

Review Article

Staging and response assessment in lymphomas: the new Lugano classification

Bruce D. Cheson

Published online: 30 March 2015

PDF Full Text (63436) Open Access

Review Article

Advanced magnetic resonance imaging in glioblastoma: a review

Gaurav Shukla, Gregory S. Alexander, Spyridon Bakas, Rahul Nikam, Kiran Talekar, Joshua D. Palmer, Wenyin Shi

Published online: 24 August 2017

PDF Full Text (57192) Open Access

Review Article

Intrahepatic cholangiocarcinoma: the AJCC/UICC 8^th edition updates

Andrew J. Lee, Yun Shin Chun

Published online: 31 October 2018

PDF Full Text (51871) Open Access

Review Articles

Percutaneous therapies of hepatocellular carcinoma—an update

Julius Chapiro, Jean-François Henri Geschwind

Published online: 16 December 2013

PDF Full Text (47557) Open Access

Review Articles

A review of hepatocellular carcinoma (HCC) staging systems

Somasundaram Subramaniam, Robin K. Kelley, Alan P. Venook

Published online: 16 December 2013

PDF Full Text (47259) Open Access

Review Article

Surgical margins in the management of extremity soft tissue sarcoma

Makoto Endo, Patrick P. Lin

Published online: 30 August 2018

PDF Full Text (46622) Open Access

Review Article

Primary extranodal B-cell lymphoma: current concepts and treatment strategies

Barbara Vannata, Emanuele Zucca

Published online: 30 March 2015

PDF Full Text (45165) Open Access

Review Articles

Colorectal cancer screening: are stool and blood based tests good enough?

Chung-Wah Wu, Joseph Jao-Yiu Sung

Published online: 10 January 2013

PDF Full Text (42531) Open Access

Review Article

Biliary tract cancers: epidemiology, molecular pathogenesis and genetic risk associations

Lorena Marcano-Bonilla, Essa A. Mohamed, Taofic Mounajjed, Lewis R. Roberts

Published online: 31 October 2016

PDF Full Text (37867) Open Access

Review Article

Classification of meningiomas—advances and controversies

Patrick N. Harter, Yannick Braun, Karl H. Plate

Published online: 20 July 2017

PDF Full Text (37775) Open Access

Review Article

BRAF, MEK and KIT inhibitors for melanoma: adverse events and their management

Elisabeth Livingstone, Lisa Zimmer, Julia Vaubel, Dirk Schadendorf

Published online: 01 September 2014

PDF Full Text (36771) Open Access

Review Article on Ovarian Cancer

Epidemiology of ovarian cancer

Patricia Gaona-Luviano, Lourdes Adriana Medina-Gaona, Kassandra Magaña-Pérez

Published online: 18 August 2020

PDF Full Text (36271) COI Form Open Access

Review Article

Imaging of soft tissue sarcomas

Dakshesh B. Patel, George R. Matcuk Jr

Published online: 30 August 2018

PDF Full Text (36273) Open Access

Review Article

Epidemiology of gallbladder cancer in India

Usha Dutta, Nikhil Bush, Dimple Kalsi, Priyanka Popli, Vinay K. Kapoor

Published online: 27 August 2019

PDF Full Text (35882) Open Access

Review Article

The timing of breast and axillary surgery after neoadjuvant chemotherapy for breast cancer

Zahraa Al-Hilli, Judy C. Boughey

Published online: 01 June 2016

PDF Full Text (35708) Open Access

Review Article

Percutaneous biliary interventions and complications in malignant bile duct obstruction

Hooman Yarmohammadi, Anne M. Covey

Published online: 31 October 2016

PDF Full Text (33522) Open Access

Review Article

Indications for adjuvant radiation therapy in breast cancer: a review of the evidence and recommendations for clinical practice

Cameron W. Swanick, Benjamin D. Smith

Published online: 01 June 2016

PDF Full Text (31791) Open Access

Review Article

Pathologic classification of “pancreatic cancers”: current concepts and challenges

Mohamed E. Mostafa, Ipek Erbarut-Seven, Burcin Pehlivanoglu, Volkan Adsay

Published online: 04 January 2018

PDF Full Text (31601) Open Access

Review Article on Neoadjuvant/adjuvant Treatment for Early Breast Cancer

Neoadjuvant treatment for HER2-positive breast cancer

Masahiro Takada, Masakazu Toi

Published online: 22 June 2020

PDF Full Text (30546) COI Form Open Access

Full Most Read article list >>

Original Article

Prostate carcinoma in transgenic Lewis rats - a tumor model for evaluation of immunological treatments

Laura E. Johnson, Jordan T. Becker, Jason A. Dubovsky, Brian M. Olson, Douglas G. McNeel

Review Article

The spectrum of clinical trials aiming at personalizing medicine

Christophe Le Tourneau, Maud Kamal, Marie Alt, Loic Verlingue, Vincent Servois, Marie-Paule Sablin, Nicolas Servant, Xavier Paoletti

Drug designs fulfilling the requirements of clinical trials aiming at personalizing medicine

Sumithra J. Mandrekar, Daniel J. Sargent

From genomic data analysis to drug development: a new generation of trials using molecular marker assessment in breast cancer

Sophie Doisneau-Sixou, Nadia Harbeck

Melanoma adjuvant therapy

Prashanth M. Thalanayar, Sanjiv S. Agarwala, Ahmad A. Tarhini

Genotyping of cutaneous melanoma

Isabella C. Glitza, Michael A. Davies

Treatment of KIT-mutated metastatic mucosal melanoma

Kevin B. Kim, Anas Alrwas

New approaches in primary central nervous system lymphoma

Eleanor Fraser, Katherine Gruenberg, James L. Rubenstein

Molecular and clinical implementations of ovarian cancer mouse avatar models

Amira A. Zayed, Sumithra J. Mandrekar, Paul Haluska

An overview of the design and conduct of the BATTLE trials

Suyu Liu, J. Jack Lee

Designing a definitive trial for adjuvant targeted therapy in genotype defined lung cancer: the ALCHEMIST trials

Ryan S. Alden, Sumithra J. Mandrekar, Geoffrey R. Oxnard

Risk- and response-adapted strategies for the management of Hodgkin lymphoma

Marcus Remer, Peter W. M. Johnson

Prognostic scores for brain metastasis patients: use in clinical practice and trial design

Vyshak Alva Venur, Manmeet S. Ahluwalia

Strategies for preservation of memory function in patients with brain metastases

Nicholas B. Dye, Vinai Gondi, Minesh P. Mehta

Management of neoplastic meningitis

Patrick Roth, Michael Weller

Design and statistical principles of the SHIVA trial

Xavier Paoletti, Bernard Asselain, Maud Kamal, Nicolas Servant, Philippe Huppé, Ivan Bieche, Christophe Le Tourneau

Autologous tracheal replacement for cancer

Dominique Fabre, Elie Fadel, Sacha Mussot, Frederic Kolb, Nicolas Leymarie, Olaf Mercier, Thierry Le Chevalier, Philippe G. Dartevelle

The staging value of sentinel lymph node biopsy for breast cancer: translating pathologic findings to clinical practice

Jean Bao, Cory Donovan, Alice Chung, Armando E. Giuliano

HER2-positive breast cancer, how far away from the cure?—on the current situation of anti-HER2 therapy in breast cancer treatment and survival of patients

Ning Liao

Training of breast surgical oncologists

Mediget Teshome, Henry M. Kuerer

The way to precision medicine of our team

Fengrui Xu, Xiaodi Wang, Zefei Jiang

Genetic testing for hereditary breast cancer in Asia—moving forward

Ava Kwong

Editorials

Can EGFR mutation status evolve with chemotherapy?

Eric S. Kim, David J. Stewart, Alok A. Khorana

Meta-Analysis

Risk of venous thromboembolism with the erythropoiesisstimulating agents (ESAs) for the treatment of cancer-associated anemia: a meta-analysis of randomized control trials

Ping Zhan, Qin Wang, Qian Qian, Li-Ke Yu

Review Articles

Prevention of colorectal cancer and dietary management

Ningqi Hou, Dezheng Huo, James J. Dignam

Stage II colon cancer

David N. Church, Rachel Midgley, David J. Kerr

Mining the ACCENT database: a review and update

Lindsay A. Renfro, Qian Shi, Daniel J. Sargent

Status of hepatocellular carcinoma in South Korea

Seung Kew Yoon, Hoo Geun Chun

Statistics in Oncology Clinical Trials

Adaptive randomized phase II design for biomarker threshold selection and independent evaluation

Lindsay A. Renfro, Christina M. Coughlin, Axel M. Grothey, Daniel J. Sargent

Adaptive clinical trial designs in oncology

Yong Zang, J. Jack Lee

Statistical aspect of translational and correlative studies in clinical trials

Herbert Pang, Xiaofei Wang

Updates on Surgical Oncology

Clinical trials in lung cancer surgery and research cooperation

Wen-Zhao Zhong, Hao-Ran Zhai, Yi-Long Wu

Original Article

A Nomogram Integrating Clinical and Multimodal Ultrasound Features for Pretreatment Prediction of HER2 Status in Breast Cancer: A Retrospective Study

Xiao-Kai Lu, Jin-Dan Li, Dong Chen, Nian-Qiu Liu, Zhi-Rui Chuan, Yin-Xi Qu, Ying-Xian Zhang, Zhi-Yao Li, Hai-Tao Chen, Xiao-Mao Luo

Published online: 29 June 2026

Original Article

Research Progress and Trends in Clinical Trials for Older People with Colorectal Cancer from 2005 to 2025: a Bibliometric Analysis

Jing Dong, Shanshan Gu, Yumei Zeng, Jiyan Shi, Yidan Hu, Zipei Zhang, Li Fu, Jiayi Song, Yun Xu

Published online: 24 June 2026

Journal Highlight more

The Chinese Clinical Oncology, indexed in MEDLINE/PubMed, ESCI, is an open-access, peer-reviewed medical journal, providing current and practical information on diagnosis, prevention and clinical investigations of cancer. Specific areas of interest include, but not limited to multimodality therapy, markers, imaging, tumor biology, pathology, chemoprevention and technical advances related to cancer.