Vol 4, No 3 (September 25, 2015): Chinese Clinical Oncology (Clinical Trials in the Genome Era—Study Designs and Endpoints, Practical Considerations - Guest Editors: Daniel Sargent, Sumithra Mandrekar and Axel Grothey)

Preface

Introduction to special issue on biomarker-based clinical trial designs in oncology
Daniel J. Sargent, Sumithra Mandrekar, Axel Grothey
Chinese Clinical Oncology  
2015;
4
(3)
:28
.

Review Article

Statistical principles for omics-based clinical trials
Michael C. Sachs
Chinese Clinical Oncology  
2015;
4
(3)
:29
.
Molecular and clinical implementations of ovarian cancer mouse avatar models
Amira A. Zayed, Sumithra J. Mandrekar, Paul Haluska
Chinese Clinical Oncology  
2015;
4
(3)
:30
.
An overview of the NCI precision medicine trials—NCI MATCH and MPACT
Khanh Do, Geraldine O’Sullivan Coyne, Alice P. Chen
Chinese Clinical Oncology  
2015;
4
(3)
:31
.
Design and statistical principles of the SHIVA trial
Xavier Paoletti, Bernard Asselain, Maud Kamal, Nicolas Servant, Philippe Huppé, Ivan Bieche, Christophe Le Tourneau
Chinese Clinical Oncology  
2015;
4
(3)
:32
.
An overview of the design and conduct of the BATTLE trials
Suyu Liu, J. Jack Lee
Chinese Clinical Oncology  
2015;
4
(3)
:33
.
The ALTERNATE trial: assessing a biomarker driven strategy for the treatment of post-menopausal women with ER+/Her2− invasive breast cancer
Vera Jean Suman, Matthew J. Ellis, Cynthia X. Ma
Chinese Clinical Oncology  
2015;
4
(3)
:34
.
The FOCUS4 design for biomarker stratified trials
Richard Kaplan
Chinese Clinical Oncology  
2015;
4
(3)
:35
.
Lung-MAP—framework, overview, and design principles
Renata Ferrarotto, Mary W. Redman, David R. Gandara, Roy S. Herbst, Vassiliki A. Papadimitrakopoulou
Chinese Clinical Oncology  
2015;
4
(3)
:36
.
Designing a definitive trial for adjuvant targeted therapy in genotype defined lung cancer: the ALCHEMIST trials
Ryan S. Alden, Sumithra J. Mandrekar, Geoffrey R. Oxnard
Chinese Clinical Oncology  
2015;
4
(3)
:37
.
Biomarker-based trials in neuro-oncology
Karla V. Ballman
Chinese Clinical Oncology  
2015;
4
(3)
:38
.

Disclosure:

The supplement “Clinical Trials in the Genome Era—Study Designs and Endpoints, Practical Considerations” was commissioned by the Editorial office, Chinese Clinical Oncology without any sponsorship or funding. Daniel Sargent, Sumithra Mandrekar and Axel Grothey served as the unpaid Guest Editors for the supplement.